Aspects of the etiology, pathogenesis and morphology of rheumatoid arthritis (literature review) 

Marija G. Fedorova, Candidate of medical sciences, associate professor, head of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: fedorovamerry@gmail.com
Ekaterina V. Komarova, Candidate of biological sciences, associate professor of the sub-department of morphology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: ekaterina-log@inbox.ru
Andrey R. Belkov, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: andreypnz15@gmail.com
Vadim A. Mishin, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: mishin_pnzgumed@mail.ru 

The purpose of the study is to analyze modern views on the etiology, pathogenesis and morphology of rheumatoid arthritis, as well as its complications. The following databases were used to write the review: «PubMed», «Google Scholar», «eLibrary»; electronic portals about medicine and biology with the use of keywords in the search: rheumatoid arthritis, joint pathology, autoimmune diseases, epidemiology of rheumatoid arthritis, rheumatic diseases. The article reflects modern ideas about the etiology and risk factors of rheumatoid arthritis, the pathogenesis of this disease, and its complications. The issues of pathomorphology, treatment and prevention at the present stage are touched upon. In conclusion, the data obtained during the analysis of scientific literature are briefly reflected, and the social and medical significance of rheumatoid arthritis at the present time is noted. 

rheumatoid arthritis, pathogenesis, morphology, autoimmune diseases 

Fedorova M. G., Komarova E. V., Belkov A. R., Mishin V.A. Aspects of the etiology, pathogenesis and morphology of rheumatoid arthritis (literature review). Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2024;(2):152–166. (In Russ.). doi: 10.21685/2072-3032-2024-2-14